Consistent Binding Capacity no matter the Therapeutics' size!

The foundational principle for chromatographic separation is using a combination of diffusive and convective forces to separate particles based on their interaction with the surfaces of the resin bead. However, this also ensures that as target molecules get larger, capacity will drop off non-linearly, meaning that a particle 10X as large will have >100-fold lower binding capacity on the same resin.

IsoTag™ is a stark deviation from this approach. By relying on the diffusion and convection of a relatively small protein reagent instead of the target, we observe consistent capacity and performance regardless of application.

To learn more please contact us here or +1 (719) 322-4394.