Concentrate and purify lentivirus in a single unit operation
Achieve high functional recovery with minimal optimization.
IsoTag™ LV Reagent
Streamlined Lentiviral Vector Purification without Chromatography
IsoTag™ LV is a specialized reagent, engineered for the challenging requirements of small and large-scale manufacturing. It enables a robust, efficient, and consistent downstream purification process for VSV-G pseudotyped lentiviral feedstreams. Purification with IsoTag™ LV does not require the use of chromatography processes nor column packing, and is designed to reduce the costs and challenges associated with scaling from R&D to commercial production.
Affinity Liquid Phase Separation (ALPS):
Novel process to deliver transformational LV purification
The binding module is a custom-designed affinity ligand for VSV-G, allowing for exquisite specificity during purification. The phase separation module is used to enable highly specific sequestration of target biologics in a complex cellular environment. The ALPS process results in high yields and product quality without size target limitations.